AZT patents
نویسندگان
چکیده
منابع مشابه
AZT: Unsafe at Any Dose?
html. file:///Users/dad/Documents/Green/AIDS/ARAS/aras.ab.ca ƒ/test/azt-integrated.html (2 of 45)3/27/2006 6:16:14 PM AZT: Unsafe at Any Dose? “1 patient [out of a grand total of 10 in this clinical trial] suffered from severe anemia resulting from ZDV [AZT] therapy” Lafeuillade A et al. Pilot study of a combination of highly active antiretroviral therapy and cytokines to induce HIV-1 remission...
متن کاملPatents or Patents Pending
An Aluminum Nitride (AlN) MEMS resonator technology has been developed, enabling massively parallel filter and oscillator arrays on a single chip. Low loss filter banks and resonator arrays covering the 10MHz10GHz frequency range have been demonstrated, as has monolithic integration with inductors and CMOS circuitry. The high level of integration enables miniature multi-band, spectrally-aware a...
متن کاملAZT as a telomerase inhibitor
Telomerase is a highly specialized reverse transcriptase (RT) and the maintenance of telomeric length is determined by this specific enzyme. The human holoenzyme telomerase is a ribonucleoprotein composed by a catalytic subunit, hTERT, an RNA component, hTR, and a group of associated proteins. Telomerase is normally expressed in embryonic cells and is repressed during adulthood. The enzyme is r...
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BIO is a trade association representing more than 1,000 biotechnology companies, academic institutions, state biotechnology centers and related organizations in all 50 U.S. states and 33 other nations. BIO members are involved in the research and development of health-care, agricultural, industrial and environmental biotechnology products. Our membership represents a complete cross section of t...
متن کاملA computational model of mitochondrial AZT metabolism.
The mechanisms of the mitochondrial toxicity of AZT (azidothymidine; zidovudine) are not clear. The two main contenders are the incorporation of phosphorylated AZT into the mtDNA (mitochondrial DNA) and the competitive inhibition of natural deoxynucleotide metabolism. We have built a computational model of AZT metabolism in mitochondria in order to better understand these toxicity mechanisms. T...
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ژورنال
عنوان ژورنال: Nature
سال: 1991
ISSN: 0028-0836,1476-4687
DOI: 10.1038/350184d0